What is autoimmune liver disease




















Mod Pathol ; 17S1 A. Autoimmune hepatitis with incidental features of bile duct injury. Hepatology ; 34 — The histological features of chronic hepatitis C and autoimmune chronic hepatitis: a comparative analysis. Hepatology ; 15 — Are bile duct lesions of primary biliary cirrhosis distinguishable from those of autoimmune hepatitis? Interobserver histological agreement on trimmed bile ducts.

J Gastroenterol ; 40 — Hepatology ; 33 — LKM1 autoantibodies in chronic hepatitis C infection: a case of molecular mimicry? Hepatology ; 42 — Epidemiology and pathogenesis of primary biliary cirrhosis. J Clin Gastroenterol ; 38 — Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: follow-up for up to 28 years. Characterisation of patients with primary biliary cirrhosis responding to long term ursodeoxycholic acid treatment. Gut ; 46 — The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis.

Liver transplantation for primary biliary cirrhosis: a long-term pathologic study. Liver Transplant ; 9 — Heterogeneous response of antimitochondrial antibodies to pyruvate dehydrogenase complex E2: the molecule versus the mimic. Kaplan M, Gershwin M. Primary biliary cirrhosis. N Engl J Med ; — Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer.

Autoantibodies against a kDa glycoprotein of the nuclear pore complex as a prognostic marker in patients with primary biliary cirrhosis. J Gastroenterol Hepatol ; 13 — Comparison of the clinicopathologic features of primary sclerosing cholangitis and primary biliary cirrhosis. Gastroenterology ; 88 — Destruction of canals of Hering in primary biliary cirrhosis. Hum Pathol ; 33 — Primary biliary cirrhosis: modalities of injury and death in biliary epithelium. Digest Liver Dis ; 33 — A scoring system for primary biliary cirrhosis and its application for variant forms of autoimmune liver disease [see comment].

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Hepatology ; 36 — A case of coexisting primary biliary cirrhosis and primary sclerosing cholangitis: a new overlap of autoimmune liver diseases. Digest Dis Sci ; 46 — The role of histologic evaluation in the diagnosis and management of autoimmune hepatitis and its variants. Download references. You can also search for this author in PubMed Google Scholar.

Correspondence to Mary K Washington. Reprints and Permissions. Close Close Alert. Although a number of autoimmune conditions may involve the liver, the three most common autoimmune liver diseases are autoimmune hepatitis, primary biliary cholangitis and primary sclerosing cholangitis. Blood testing is often the first step to diagnosing autoimmune liver diseases because many patients do not show symptoms until the disease has progressed to cirrhosis or liver failure. Your doctor may request diagnostic imaging of your liver and may also perform a liver biopsy.

Individuals with another autoimmune disease may be at higher risk for autoimmune liver diseases. Treatments for autoimmune liver disease vary depending on the specific diagnosis. Learn More. Search Submit Search.

Find a Doctor. Sign up now. If you are experiencing a medical emergency, call Close Alert. There are many different types of liver disease. But no matter what type you have, the damage to your liver is likely to progress in a similar way.

Whether your liver is infected with a virus, injured by chemicals, or under attack from your own immune system, the basic danger is the same — that your liver will become so damaged that it can no longer work to keep you alive. Cirrhosis, liver cancer, and liver failure are serious conditions that can threaten your life. Once you have reached these stages of liver disease, your treatment options may be very limited.

If you are treated successfully at these stages, your liver may have a chance to heal itself and recover. Talk to your doctor about liver disease.

Find out if you are at risk or if you should undergo any tests or vaccinations. Learn More…. Clinical trials are research studies that test how well new medical approaches work in people.

Before an experimental treatment can be tested on human subjects in a clinical trial, it must have shown benefit in laboratory testing or animal research studies. The most promising treatments are then moved into clinical trials, with the goal of identifying new ways to safely and effectively prevent, screen for, diagnose, or treat a disease. Speak with your doctor about the ongoing progress and results of these trials to get the most up-to-date information on new treatments.

Participating in a clinical trial is a great way to contribute to curing, preventing and treating liver disease and its complications. Start your search here to find clinical trials that need people like you. Autoimmune Hepatitis.

Facts at-a-Glance. Autoimmune Hepatitis is a serious condition that may worsen over time if not treated. Autoimmune Hepatitis can lead to cirrhosis and liver failure. Autoimmune Hepatitis is a rare disorder that affects females 4 times as often as males. Information for the Newly Diagnosed.

What causes autoimmune hepatitis? What are the symptoms and complications of autoimmune hepatitis? How is autoimmune hepatitis diagnosed? How is autoimmune hepatitis treated? Who is at risk for autoimmune hepatitis?

Questions to Ask Your Doctor. Are my symptoms that I am experiencing if you are such as fatigue and lethargy due to AIH?



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